Peptide therapy is becoming well known within the public sector. For example most effective skin creams on the market will contain peptides to help skin stay youthful.
Athletes have been aware of Peptide use for decades to boost performance and recovery.
Peptides are composed of amino acids of which our bodies contain over 7000 and are found in all cells of the body.
Peptide therapy refers to restoring the number of peptides to stimulate cellular growth systems within our bodies for specific targets we want to achieve.
Using a specific protocol we can produce a specific reaction either hormonal or enzymatic to treat a variety of conditions.
Typically administration is by SubQ or IM injection, nasal spray, Sublingual drops, capsules and topical creams.
Benefits of peptide therapy include:
· Boost hormonal and enzyme levels
· Reduce the signs of aging by improving skin texture
· Helps to stimulate fat burning, reduce cellulite and maintain healthy weight management
· Elevates athletic performance
· Proliferates muscle mass
· Helps reverse sexual dysfunction and increase libido
· Increase energy
· Improves mental health
· Promote healthy body function
· Stimulates healing, repair and regeneration processes of the body
· Curbs joint and muscle pain
· Enhance cognitive function and memory
· Can help safeguard against age related diseases
Peptide therapy has been shown to be an effective and generally safe practice with side effects typically being dose dependent.
There is no best peptide therapy as its effectiveness is down to the individual’s condition and specific targets.
It’s advised to consult with a healthcare professional before peptide therapy use, as peptides classification is research products.
Learn MorePeptides come to you in a lyophilised, freeze-dried form. Like this, the peptides will remain stable for around 30 days at room temperature. Although if not going to use immediately it is recommended to store in a refrigerator. If they are not going to be used within this time then they can be stored in a freezer where they will remain stablefor approximately 48 months.
Please ensure that your freezer is not ‘frost free’ or ‘auto defrosting’ as constant freeze/thaw cycles will degrade the peptides over time.
Storage of your peptides once you have mixed them.
Once the peptides have been mixed or reconstituted into a liquid solution they must be refrigerated at a temperature between 2-8c.
If stored at room temperature some peptides may begin to degrade after as little as 24 hours.
For Your Information
All our peptides are stored at -2 / -8 until the day of dispatch.
When mixing, apply the water slowly and carefully to the powder avoiding making bubbles. Extreme care needs to be practiced when reconstituting as the amino acid structures are very fragile which makes incorrect techniques for reconstituting can break these structures.
Do not shake peptides aggressively if any powder is left in the vial after a few minutes, as this also can break the fragile structure of the amino acids effectively rendering them useless and ineffective . Just gently swirl till mixed, great care needs to be used.
When storing in the refrigerator make sure they are in a stable place.
Storage of your peptides once you have mixed them.
Once the peptides have been mixed or reconstituted into a liquid solution they must be refrigerated at a temperature of between 2-8c.
If stored at room temperature some peptides may begin to degrade after as little as 24 hours.
For Your Information
All our peptides are stored at -2 / -8 oc until the day of dispatch.
When mixing, apply the water slowly and carefully to the powder avoiding making bubbles .Extreme care needs to be practiced when reconstituting as the amino acid structures are very fragile which makes incorrect techniques for reconstituting can break these structures.
Do not shake peptides aggressively if any powder is left in the vial after a few minutes, as this also can break the fragile structure of the amino acids effectively rendering them useless and ineffective . Just gently swirl till mixed, great care needs to be used.
When storing in the refrigerator make sure they are in a stable place.
If for some reason you don’t intend using the peptides for some time you can store them in the freezer
Learn More HerePeptides are stored in a lyophilized (afreeze dried fine powder) state and so need reconstitution before they can be used. Bacteriostatic water is generally used although some peptides for example IGF1 type peptides Acetic acid is used. Both extends the storage life of the reconstituted product and also allows multiple doses to be drawn up out of the vial, which is more convenient and cost-effective in a research context. However, for IGF1 DES and IGF1 Long R3, Acetic Acid 0.9% is favoured for reconstitution due to buffering issues and poor solubility when using bacteriostatic water.
Looking at the various diluting agents inmore detail:
Bacteriostatic Water
This is a sterile, nonpyrogenic preparation of water for injection containing 0.9% (9 mg/mL) of benzyl alcohol added as a bacteriostatic preservative. It is supplied in a multiple-dose container from which repeated withdrawals may be made to dilute or dissolve drugs for injection. The pH is 5.7 (4.5 to 7.0). Bacteriostatic water is used to reconstitute all peptides, although for IGF1 derivatives Acetic Acid is recommended.
Acetic Acid Water
Acetic acid water benefits over Bacteriostatic water as it can help increase solubility of certain peptides and keep them more stable.
Learn MoreWith the popularity of peptides becoming more aware mainstream public market so are the different ways to be administered. The most effect for most peptides is by injection either subcutaneously or intra muscularly. The type of needle and syringe needed should not make even the most needle phobic individual squeamish as the correct type is what is known as microfine, ideally with an 8mm microfine pin. The administered either subcutaneously or intra muscularly the following information explains both processes
Subcutaneous Injection:
Subcutaneous injection is administered on to fatty tissues under the skin. the fatty layer is situated immediately beneath the skin and contains few blood vessels. the subcutaneous shot is shallower compared to injections on muscle tissues. Subcutaneous injection is suitable for administering medications that are slowly absorbed in the bloodstream. Examples of such medication is insulin, some fertility drugs, and blood thinners. Subcutaneous injection is safe and requires little force as compared to intramuscular injections. The few blood vessels on this fat layer make it ideal for drugs that need to be absorbed and used slowly in the body. Mostly, the drugs that are to be administered daily are designed suitably for subcutaneous injection since it’s simple.
How to perform subcutaneous injection:
Choose areas such as thigh, top of buttocks, back of the arm or the abdomen. These areas are known to be fatty. When you are doing the injections severally, it’s important to rotate the injection areas to for complete healing. Don’t inject one area frequently.
• Ensure your hands are clean, and clean the injection area too. Use alcohol pad to clean. After clean, allow the area to dry.
• Use the needle to draw medicine into the syringe. Usually, you turn the vial upside down and pull the plunger to suck the drug. Ensure the syringe is free of bubbles by tapping it.
• Pinch a 2-inch thick skin of the fatty area within your thumb and a finger.
• Slide the needle at 90 degrees into the skin.
• Push the plunger quickly.
• Remove and safely dispose of the needle.
Intramuscular: Intramuscular injections are delivered into the muscle:
Intramuscular injection is an injection method used to deposit compounds into the muscle tissue. The method is suitable for administering medication that need to be absorbed quickly in the blood. The muscle tissue has less pain sensing nerves making it less painful. Examples of drugs administered using intramuscular injection include antibiotics, vaccinations and hormones. Body areas on which IM can be done include shoulder muscle, thigh muscles, muscles on the hip.
Steps of intramuscular injection:
• Choose the site that is most suitable forthe injection depending on your comfort and stability.
• Ensure you have done the injection dosage correctly.
• Prepare the medication following the recommended procedures and medical instructions.
• When ready, use alcohol pads to clean theinjection area and allow it to dry.
• Inject the selected and cleaned area.
• After the injection removes the needle and disposes of it safely.
Other ways of peptide administration
Nasal Pathway:
Nasal drug delivery system is a promising alternative route of administration for the several systemically acting drugs with poor bio availability and it has advantages in terms of improved patient acceptability and an alternative option to injecting, but still providing adirect pathway into the bloodstream
Sublingual Pathway:
Sublingual (abbreviated SL), from the Latinfor "under the tongue", refers to the pharmacological route of administration by which substances diffuse into the blood through tissues under the tongue. Many compounds and drugs are absorbed through sublingual administration, including cardiovascular drugs, steroids, barbiturates, benzodiazepines, opioid analgesics, THC, CBD, some proteins and increasingly vitamins and minerals.
How SL works
When a chemical comes in contact with the mucous membrane beneath the tongue, it is absorbed. Because the connective tissue beneath the epithelium contains a profusion of capillaries, the substance then diffuses into them and enters the venous circulation. In contrast, substances absorbed in the intestines are subject to first-pass metabolism in the liver before entering the general circulation.
Sublingual administration has certain advantages over oral administration. Being more direct, it is often faster onset of action, and it ensures that the substance will risk degradation only by salivary enzymes before entering the bloodstream, whereas orally administered drugs must survive passage through the hostile environment of the gastrointestinal tract, which risks degrading them by up to 25%, by either stomach acid or bile, or by enzymes such as monoamine oxidase (MAO). Furthermore, after absorption from the gastrointestinal tract, such drugs must pass to the liver, where they may be extensively altered; this is known as the first pass effect of drug metabolism. Due to the digestive activity of the stomach and intestines, the oral route is unsuitable for certain substances.
Capsules:
The oral administration of therapeutic peptides and proteins is favoured from a patient and commercial point of view for a market that do not favour injectable or nasal pathway. Even though oral administration of peptides are effective when used correctly they are the least effective pathway due to having to pass through the digestive tract.
Learn MoreUK Domestic Delivery (including Northern Ireland)
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